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v) Finally, epigenetic modifications since the down‐stream consequence of Sig1R and five‐HT2A (and/or other serotonin receptor) activation may well contribute to the extended‐term immunomodulatory and Professional‐neuroplastic effects of five‐MeO‐copyright and possibly of other tryptamines. This system could underlie the observed, very long‐phrase beneficial outcomes of a single dose of serotonergic tryptamine about the signs and symptoms of despair and stress.
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